| Sikeston to Candler-McAfee (Georgia) | 370.65 mi (596.50 km) |
| Sikeston to Caño Martin Peña (Puerto Rico) | 1,913.45 mi (3,079.41 km) |
| Sikeston to Cañon City (Colorado) | 860.71 mi (1,385.17 km) |
| Sikeston to Canóvanas (Puerto Rico) | 1,923.30 mi (3,095.25 km) |
| Sikeston to Canton (Georgia) | 339.53 mi (546.42 km) |
| Sikeston to Canton (Illinois) | 255.28 mi (410.84 km) |
| Sikeston to Canton (Mississippi) | 297.33 mi (478.51 km) |
| Sikeston to Canton (Ohio) | 518.41 mi (834.31 km) |
| Sikeston to Canyon (Texas) | 701.61 mi (1,129.12 km) |
| Sikeston to Canyon Lake (California) | 1,570.76 mi (2,527.90 km) |
| Sikeston to Canyon Lake (Texas) | 695.77 mi (1,119.73 km) |
| Sikeston to Cape Coral (Florida) | 835.68 mi (1,344.90 km) |
| Sikeston to Cape Girardeau (Missouri) | 29.44 mi (47.38 km) |
| Sikeston to Carbondale (Illinois) | 61.17 mi (98.45 km) |
| Sikeston to Carlisle (Pennsylvania) | 706.62 mi (1,137.20 km) |
