| Sikeston to Carrollwood (Florida) | 735.66 mi (1,183.93 km) |
| Sikeston to Carson (California) | 1,622.87 mi (2,611.76 km) |
| Sikeston to Carson City (Nevada) | 1,641.56 mi (2,641.83 km) |
| Sikeston to Carteret (New Jersey) | 865.04 mi (1,392.14 km) |
| Sikeston to Cartersville (Georgia) | 328.25 mi (528.27 km) |
| Sikeston to Carthage (Missouri) | 261.82 mi (421.36 km) |
| Sikeston to Cary (Illinois) | 374.92 mi (603.38 km) |
| Sikeston to Cary (North Carolina) | 603.86 mi (971.82 km) |
| Sikeston to Casa de Oro-Mount Helix (California) | 1,573.30 mi (2,531.97 km) |
| Sikeston to Casa Grande (Arizona) | 1,283.21 mi (2,065.12 km) |
| Sikeston to Casas Adobes (Arizona) | 1,255.03 mi (2,019.77 km) |
| Sikeston to Cascades (Virginia) | 680.56 mi (1,095.26 km) |
| Sikeston to Casper (Wyoming) | 975.91 mi (1,570.58 km) |
| Sikeston to Casselberry (Florida) | 743.23 mi (1,196.12 km) |
| Sikeston to Castaic (California) | 1,632.11 mi (2,626.62 km) |
