| Sikeston to Central Point (Oregon) | 1,801.22 mi (2,898.78 km) |
| Sikeston to Centralia (Illinois) | 115.92 mi (186.56 km) |
| Sikeston to Centralia (Washington) | 1,831.83 mi (2,948.05 km) |
| Sikeston to Centreville (Virginia) | 675.76 mi (1,087.53 km) |
| Sikeston to Ceres (California) | 1,718.39 mi (2,765.48 km) |
| Sikeston to Cerritos (California) | 1,611.95 mi (2,594.19 km) |
| Sikeston to Chalco (Nebraska) | 459.76 mi (739.92 km) |
| Sikeston to Chalmette (Louisiana) | 480.11 mi (772.67 km) |
| Sikeston to Chambersburg (Pennsylvania) | 678.80 mi (1,092.43 km) |
| Sikeston to Chamblee (Georgia) | 362.80 mi (583.87 km) |
| Sikeston to Champaign (Illinois) | 234.12 mi (376.78 km) |
| Sikeston to Champlin (Minnesota) | 605.58 mi (974.58 km) |
| Sikeston to Chandler (Arizona) | 1,280.07 mi (2,060.07 km) |
| Sikeston to Chanhassen (Minnesota) | 588.28 mi (946.74 km) |
| Sikeston to Channahon (Illinois) | 321.34 mi (517.15 km) |
