| Sikeston to Colton (California) | 1,567.49 mi (2,522.63 km) |
| Sikeston to Columbia (Illinois) | 113.96 mi (183.40 km) |
| Sikeston to Columbia (Maryland) | 710.19 mi (1,142.95 km) |
| Sikeston to Columbia (Missouri) | 206.34 mi (332.08 km) |
| Sikeston to Columbia (Pennsylvania) | 740.23 mi (1,191.29 km) |
| Sikeston to Columbia (South Carolina) | 526.57 mi (847.43 km) |
| Sikeston to Columbia (Tennessee) | 166.17 mi (267.42 km) |
| Sikeston to Columbia Heights (Minnesota) | 595.27 mi (958.00 km) |
| Sikeston to Columbine (Colorado) | 859.51 mi (1,383.25 km) |
| Sikeston to Columbus (Georgia) | 403.61 mi (649.54 km) |
| Sikeston to Columbus (Indiana) | 256.17 mi (412.27 km) |
| Sikeston to Columbus (Mississippi) | 242.59 mi (390.41 km) |
| Sikeston to Columbus (Nebraska) | 521.27 mi (838.91 km) |
| Sikeston to Columbus (Ohio) | 416.45 mi (670.22 km) |
| Sikeston to Commack (New York) | 917.18 mi (1,476.06 km) |
