| Sikeston to Cordele (Georgia) | 475.15 mi (764.67 km) |
| Sikeston to Corinth (Mississippi) | 146.75 mi (236.18 km) |
| Sikeston to Corinth (Texas) | 495.78 mi (797.87 km) |
| Sikeston to Cornelius (North Carolina) | 495.09 mi (796.77 km) |
| Sikeston to Cornelius (Oregon) | 1,823.52 mi (2,934.68 km) |
| Sikeston to Corning (New York) | 759.38 mi (1,222.10 km) |
| Sikeston to Corona (California) | 1,584.24 mi (2,549.58 km) |
| Sikeston to Coronado (California) | 1,586.02 mi (2,552.45 km) |
| Sikeston to Corpus Christi (Texas) | 778.71 mi (1,253.22 km) |
| Sikeston to Corsicana (Texas) | 513.16 mi (825.85 km) |
| Sikeston to Cortland (New York) | 813.14 mi (1,308.62 km) |
| Sikeston to Corvallis (Oregon) | 1,827.54 mi (2,941.14 km) |
| Sikeston to Coshocton (Ohio) | 478.50 mi (770.07 km) |
| Sikeston to Costa Mesa (California) | 1,607.18 mi (2,586.50 km) |
| Sikeston to Coto de Caza (California) | 1,590.44 mi (2,559.56 km) |
