| Sikeston to Cullman (Alabama) | 242.59 mi (390.41 km) |
| Sikeston to Culpeper (Virginia) | 642.60 mi (1,034.17 km) |
| Sikeston to Culver City (California) | 1,627.54 mi (2,619.28 km) |
| Sikeston to Cumberland (Maryland) | 617.28 mi (993.42 km) |
| Sikeston to Cupertino (California) | 1,780.08 mi (2,864.76 km) |
| Sikeston to Cutler Bay (Florida) | 952.42 mi (1,532.78 km) |
| Sikeston to Cutlerville (Michigan) | 460.71 mi (741.44 km) |
| Sikeston to Cuyahoga Falls (Ohio) | 523.94 mi (843.20 km) |
| Sikeston to Cypress (California) | 1,611.24 mi (2,593.05 km) |
| Sikeston to Cypress Gardens (Florida) | 766.71 mi (1,233.91 km) |
| Sikeston to Cypress Lake (Florida) | 844.94 mi (1,359.80 km) |
| Sikeston to D'Iberville (Mississippi) | 444.95 mi (716.08 km) |
| Sikeston to Dakota Ridge (Colorado) | 863.23 mi (1,389.24 km) |
| Sikeston to Dale City (Virginia) | 679.09 mi (1,092.88 km) |
| Sikeston to Dallas (Georgia) | 336.91 mi (542.21 km) |
