| Sikeston to Darby (Pennsylvania) | 802.57 mi (1,291.62 km) |
| Sikeston to Dardenne Prairie (Missouri) | 143.57 mi (231.05 km) |
| Sikeston to Darien (Illinois) | 346.53 mi (557.68 km) |
| Sikeston to Davenport (Iowa) | 327.30 mi (526.74 km) |
| Sikeston to Davidson (North Carolina) | 497.99 mi (801.43 km) |
| Sikeston to Davie (Florida) | 925.07 mi (1,488.75 km) |
| Sikeston to Davis (California) | 1,751.90 mi (2,819.42 km) |
| Sikeston to Dayton (Nevada) | 1,631.31 mi (2,625.33 km) |
| Sikeston to Dayton (Ohio) | 353.83 mi (569.43 km) |
| Sikeston to Daytona Beach (Florida) | 723.06 mi (1,163.66 km) |
| Sikeston to De Pere (Wisconsin) | 527.28 mi (848.57 km) |
| Sikeston to De Witt (New York) | 830.28 mi (1,336.21 km) |
| Sikeston to Dearborn (Michigan) | 505.45 mi (813.45 km) |
| Sikeston to Dearborn Heights (Michigan) | 503.37 mi (810.09 km) |
| Sikeston to DeBary (Florida) | 731.28 mi (1,176.88 km) |
