| Sikeston to Dixon (California) | 1,757.48 mi (2,828.39 km) |
| Sikeston to Dixon (Illinois) | 342.65 mi (551.44 km) |
| Sikeston to Dobbs Ferry (New York) | 889.93 mi (1,432.20 km) |
| Sikeston to Doctor Phillips (Florida) | 748.77 mi (1,205.03 km) |
| Sikeston to Dodge City (Kansas) | 575.98 mi (926.95 km) |
| Sikeston to Dolton (Illinois) | 344.54 mi (554.48 km) |
| Sikeston to Donna (Texas) | 893.10 mi (1,437.31 km) |
| Sikeston to Dorado (Puerto Rico) | 1,901.73 mi (3,060.53 km) |
| Sikeston to Doral (Florida) | 937.87 mi (1,509.36 km) |
| Sikeston to Doraville (Georgia) | 363.23 mi (584.56 km) |
| Sikeston to Dothan (Alabama) | 457.87 mi (736.86 km) |
| Sikeston to Douglas (Arizona) | 1,200.62 mi (1,932.21 km) |
| Sikeston to Douglas (Georgia) | 534.67 mi (860.48 km) |
| Sikeston to Douglasville (Georgia) | 350.70 mi (564.39 km) |
| Sikeston to Dover (Delaware) | 780.80 mi (1,256.58 km) |
