| Sikeston to El Segundo (California) | 1,629.45 mi (2,622.35 km) |
| Sikeston to El Sobrante (California) | 1,578.37 mi (2,540.15 km) |
| Sikeston to Eldersburg (Maryland) | 707.61 mi (1,138.78 km) |
| Sikeston to Elfers (Florida) | 719.77 mi (1,158.36 km) |
| Sikeston to Elgin (Illinois) | 362.34 mi (583.14 km) |
| Sikeston to Elizabeth (New Jersey) | 868.14 mi (1,397.13 km) |
| Sikeston to Elizabeth City (North Carolina) | 741.23 mi (1,192.89 km) |
| Sikeston to Elizabethton (Tennessee) | 409.34 mi (658.76 km) |
| Sikeston to Elizabethtown (Kentucky) | 211.61 mi (340.55 km) |
| Sikeston to Elizabethtown (Pennsylvania) | 736.74 mi (1,185.67 km) |
| Sikeston to Elk City (Oklahoma) | 558.63 mi (899.03 km) |
| Sikeston to Elk Grove (California) | 1,734.02 mi (2,790.63 km) |
| Sikeston to Elk Grove Village (Illinois) | 363.90 mi (585.65 km) |
| Sikeston to Elk Plain (Washington) | 1,807.73 mi (2,909.26 km) |
| Sikeston to Elk River (Minnesota) | 619.03 mi (996.23 km) |
