| Sikeston to Elkhart (Indiana) | 384.42 mi (618.67 km) |
| Sikeston to Elkhorn (Wisconsin) | 403.63 mi (649.57 km) |
| Sikeston to Elko (Nevada) | 1,429.13 mi (2,299.96 km) |
| Sikeston to Elkridge (Maryland) | 716.27 mi (1,152.73 km) |
| Sikeston to Elkton (Maryland) | 769.46 mi (1,238.33 km) |
| Sikeston to Ellensburg (Washington) | 1,723.26 mi (2,773.32 km) |
| Sikeston to Ellicott City (Maryland) | 712.34 mi (1,146.40 km) |
| Sikeston to Elmhurst (Illinois) | 357.23 mi (574.90 km) |
| Sikeston to Elmira (New York) | 769.41 mi (1,238.24 km) |
| Sikeston to Elmont (New York) | 893.44 mi (1,437.85 km) |
| Sikeston to Elmwood Park (Illinois) | 360.63 mi (580.37 km) |
| Sikeston to Elmwood Park (New Jersey) | 875.48 mi (1,408.95 km) |
| Sikeston to Elon (North Carolina) | 562.20 mi (904.77 km) |
| Sikeston to Eloy (Arizona) | 1,277.81 mi (2,056.43 km) |
| Sikeston to Elwood (New York) | 914.38 mi (1,471.55 km) |
