| Sikeston to Excelsior Springs (Missouri) | 304.41 mi (489.89 km) |
| Sikeston to Exeter (California) | 1,633.72 mi (2,629.21 km) |
| Sikeston to Fair Lawn (New Jersey) | 876.11 mi (1,409.96 km) |
| Sikeston to Fair Oaks (California) | 1,725.04 mi (2,776.18 km) |
| Sikeston to Fair Oaks (Virginia) | 680.28 mi (1,094.81 km) |
| Sikeston to Fairbanks (Alaska) | 3,018.33 mi (4,857.54 km) |
| Sikeston to Fairborn (Ohio) | 363.15 mi (584.43 km) |
| Sikeston to Fairburn (Georgia) | 364.13 mi (586.00 km) |
| Sikeston to Fairfax (Virginia) | 683.31 mi (1,099.68 km) |
| Sikeston to Fairfax Station (Virginia) | 680.85 mi (1,095.73 km) |
| Sikeston to Fairfield (California) | 1,770.25 mi (2,848.94 km) |
| Sikeston to Fairfield (Ohio) | 322.12 mi (518.40 km) |
| Sikeston to Fairhope (Alabama) | 450.52 mi (725.05 km) |
| Sikeston to Fairland (Maryland) | 703.97 mi (1,132.93 km) |
| Sikeston to Fairmont (Minnesota) | 532.78 mi (857.43 km) |
