| Sikeston to Frederick (Colorado) | 859.86 mi (1,383.81 km) |
| Sikeston to Frederick (Maryland) | 683.79 mi (1,100.45 km) |
| Sikeston to Fredericksburg (Texas) | 702.91 mi (1,131.22 km) |
| Sikeston to Fredericksburg (Virginia) | 669.14 mi (1,076.87 km) |
| Sikeston to Frederickson (Washington) | 1,808.10 mi (2,909.85 km) |
| Sikeston to Freeport (Illinois) | 373.37 mi (600.88 km) |
| Sikeston to Freeport (New York) | 899.00 mi (1,446.80 km) |
| Sikeston to Freeport (Texas) | 642.37 mi (1,033.79 km) |
| Sikeston to Fremont (California) | 1,774.48 mi (2,855.75 km) |
| Sikeston to Fremont (Nebraska) | 485.13 mi (780.74 km) |
| Sikeston to Fremont (Ohio) | 464.19 mi (747.04 km) |
| Sikeston to French Valley (California) | 1,563.88 mi (2,516.83 km) |
| Sikeston to Fresno (California) | 1,663.36 mi (2,676.92 km) |
| Sikeston to Fresno (Texas) | 610.82 mi (983.01 km) |
| Sikeston to Fridley (Minnesota) | 597.80 mi (962.06 km) |
