| Sikeston to Friendly (Maryland) | 700.43 mi (1,127.23 km) |
| Sikeston to Friendswood (Texas) | 603.71 mi (971.58 km) |
| Sikeston to Frisco (Texas) | 483.45 mi (778.03 km) |
| Sikeston to Front Royal (Virginia) | 637.02 mi (1,025.18 km) |
| Sikeston to Fruit Cove (Florida) | 655.91 mi (1,055.59 km) |
| Sikeston to Fruita (Colorado) | 1,051.68 mi (1,692.51 km) |
| Sikeston to Fruitville (Florida) | 780.14 mi (1,255.51 km) |
| Sikeston to Fuller Heights (Florida) | 760.63 mi (1,224.11 km) |
| Sikeston to Fullerton (California) | 1,603.88 mi (2,581.19 km) |
| Sikeston to Fullerton (Pennsylvania) | 801.69 mi (1,290.19 km) |
| Sikeston to Fulshear (Texas) | 615.31 mi (990.25 km) |
| Sikeston to Fulton (Missouri) | 187.43 mi (301.64 km) |
| Sikeston to Fulton (New York) | 824.34 mi (1,326.65 km) |
| Sikeston to Fuquay-Varina (North Carolina) | 608.62 mi (979.48 km) |
| Sikeston to Gadsden (Alabama) | 282.68 mi (454.93 km) |
