| Sikeston to La Crescenta-Montrose (California) | 1,614.56 mi (2,598.38 km) |
| Sikeston to La Crosse (Wisconsin) | 487.09 mi (783.90 km) |
| Sikeston to La Grande (Oregon) | 1,583.81 mi (2,548.90 km) |
| Sikeston to La Grange (Illinois) | 352.15 mi (566.73 km) |
| Sikeston to La Grange Park (Illinois) | 353.75 mi (569.30 km) |
| Sikeston to La Habra (California) | 1,604.37 mi (2,581.98 km) |
| Sikeston to La Homa (Texas) | 895.36 mi (1,440.93 km) |
| Sikeston to La Marque (Texas) | 606.03 mi (975.32 km) |
| Sikeston to La Mesa (California) | 1,576.01 mi (2,536.34 km) |
| Sikeston to La Mirada (California) | 1,608.03 mi (2,587.88 km) |
| Sikeston to La Palma (California) | 1,610.74 mi (2,592.23 km) |
| Sikeston to La Porte (Indiana) | 360.58 mi (580.30 km) |
| Sikeston to La Porte (Texas) | 589.73 mi (949.08 km) |
| Sikeston to La Presa (California) | 1,576.31 mi (2,536.82 km) |
| Sikeston to La Puente (California) | 1,602.56 mi (2,579.07 km) |
