| Sikeston to La Quinta (California) | 1,517.07 mi (2,441.49 km) |
| Sikeston to La Riviera (California) | 1,731.26 mi (2,786.19 km) |
| Sikeston to La Vergne (Tennessee) | 178.64 mi (287.49 km) |
| Sikeston to La Verne (California) | 1,590.86 mi (2,560.24 km) |
| Sikeston to La Vista (Nebraska) | 456.94 mi (735.38 km) |
| Sikeston to Lacey (Washington) | 1,827.54 mi (2,941.14 km) |
| Sikeston to Lackawanna (New York) | 701.57 mi (1,129.07 km) |
| Sikeston to Laconia (New Hampshire) | 1,058.15 mi (1,702.92 km) |
| Sikeston to Ladera Ranch (California) | 1,594.42 mi (2,565.97 km) |
| Sikeston to Ladson (South Carolina) | 599.57 mi (964.92 km) |
| Sikeston to Lady Lake (Florida) | 706.48 mi (1,136.96 km) |
| Sikeston to Lafayette (California) | 1,778.15 mi (2,861.66 km) |
| Sikeston to Lafayette (Colorado) | 865.28 mi (1,392.54 km) |
| Sikeston to Lafayette (Indiana) | 283.90 mi (456.89 km) |
| Sikeston to Lafayette (Louisiana) | 482.30 mi (776.18 km) |
