| Sikeston to Live Oak (Texas) | 715.24 mi (1,151.06 km) |
| Sikeston to Livermore (California) | 1,760.76 mi (2,833.67 km) |
| Sikeston to Livingston (California) | 1,707.58 mi (2,748.08 km) |
| Sikeston to Livonia (Michigan) | 504.04 mi (811.17 km) |
| Sikeston to Lochearn (Maryland) | 718.60 mi (1,156.47 km) |
| Sikeston to Lockhart (Florida) | 740.94 mi (1,192.43 km) |
| Sikeston to Lockhart (Texas) | 672.15 mi (1,081.73 km) |
| Sikeston to Lockport (Illinois) | 335.61 mi (540.11 km) |
| Sikeston to Lockport (New York) | 720.54 mi (1,159.59 km) |
| Sikeston to Lodi (California) | 1,731.51 mi (2,786.60 km) |
| Sikeston to Lodi (New Jersey) | 877.03 mi (1,411.44 km) |
| Sikeston to Logan (Utah) | 1,232.10 mi (1,982.88 km) |
| Sikeston to Logansport (Indiana) | 318.59 mi (512.73 km) |
| Sikeston to Loganville (Georgia) | 383.65 mi (617.42 km) |
| Sikeston to Loma Linda (California) | 1,563.46 mi (2,516.15 km) |
