| Sikeston to Los Alamitos (California) | 1,612.76 mi (2,595.48 km) |
| Sikeston to Los Alamos (New Mexico) | 930.12 mi (1,496.88 km) |
| Sikeston to Los Altos (California) | 1,782.23 mi (2,868.22 km) |
| Sikeston to Los Angeles (California) | 1,626.13 mi (2,617.01 km) |
| Sikeston to Los Banos (California) | 1,717.30 mi (2,763.72 km) |
| Sikeston to Los Gatos (California) | 1,776.11 mi (2,858.38 km) |
| Sikeston to Los Lunas (New Mexico) | 972.11 mi (1,564.46 km) |
| Sikeston to Los Osos (California) | 1,739.57 mi (2,799.56 km) |
| Sikeston to Loudoun Valley Estates (Virginia) | 673.58 mi (1,084.02 km) |
| Sikeston to Louisville (Colorado) | 867.33 mi (1,395.83 km) |
| Sikeston to Louisville (Kentucky) | 233.27 mi (375.41 km) |
| Sikeston to Lovejoy (Georgia) | 380.93 mi (613.04 km) |
| Sikeston to Loveland (Colorado) | 868.59 mi (1,397.86 km) |
| Sikeston to Loveland (Ohio) | 332.54 mi (535.18 km) |
| Sikeston to Loves Park (Illinois) | 377.93 mi (608.22 km) |
