| Sikeston to Mattoon (Illinois) | 191.05 mi (307.47 km) |
| Sikeston to Mauldin (South Carolina) | 433.01 mi (696.85 km) |
| Sikeston to Maumee (Ohio) | 452.86 mi (728.80 km) |
| Sikeston to Maumelle (Arkansas) | 211.00 mi (339.57 km) |
| Sikeston to Mayagüez (Puerto Rico) | 1,876.71 mi (3,020.28 km) |
| Sikeston to Mayfield Heights (Ohio) | 540.07 mi (869.16 km) |
| Sikeston to Mays Chapel (Maryland) | 723.80 mi (1,164.84 km) |
| Sikeston to Maywood (California) | 1,616.31 mi (2,601.19 km) |
| Sikeston to Maywood (Illinois) | 357.40 mi (575.17 km) |
| Sikeston to McAlester (Oklahoma) | 371.62 mi (598.07 km) |
| Sikeston to McAllen (Texas) | 894.81 mi (1,440.05 km) |
| Sikeston to McCalla (Alabama) | 286.66 mi (461.34 km) |
| Sikeston to McComb (Mississippi) | 393.03 mi (632.52 km) |
| Sikeston to McDonough (Georgia) | 388.47 mi (625.18 km) |
| Sikeston to McFarland (California) | 1,647.10 mi (2,650.75 km) |
