| Sikeston to McHenry (Illinois) | 383.02 mi (616.41 km) |
| Sikeston to McKeesport (Pennsylvania) | 577.27 mi (929.03 km) |
| Sikeston to McKinleyville (California) | 1,863.39 mi (2,998.84 km) |
| Sikeston to McKinney (Texas) | 474.29 mi (763.29 km) |
| Sikeston to McLean (Virginia) | 689.78 mi (1,110.09 km) |
| Sikeston to McMinnville (Oregon) | 1,827.79 mi (2,941.55 km) |
| Sikeston to McMinnville (Tennessee) | 227.59 mi (366.27 km) |
| Sikeston to McNair (Virginia) | 678.30 mi (1,091.62 km) |
| Sikeston to McPherson (Kansas) | 453.36 mi (729.61 km) |
| Sikeston to Mead Valley (California) | 1,569.31 mi (2,525.56 km) |
| Sikeston to Meadow Woods (Florida) | 758.34 mi (1,220.43 km) |
| Sikeston to Meadowbrook (Virginia) | 667.65 mi (1,074.48 km) |
| Sikeston to Meadville (Pennsylvania) | 602.19 mi (969.14 km) |
| Sikeston to Mebane (North Carolina) | 575.34 mi (925.92 km) |
| Sikeston to Mechanicsville (Virginia) | 674.13 mi (1,084.91 km) |
