| Sikeston to Medford (Massachusetts) | 1,052.13 mi (1,693.23 km) |
| Sikeston to Medford (New York) | 932.10 mi (1,500.06 km) |
| Sikeston to Medford (Oregon) | 1,798.26 mi (2,894.02 km) |
| Sikeston to Medina (Ohio) | 507.55 mi (816.83 km) |
| Sikeston to Medulla (Florida) | 759.03 mi (1,221.54 km) |
| Sikeston to Mehlville (Missouri) | 118.55 mi (190.78 km) |
| Sikeston to Melbourne (Florida) | 798.07 mi (1,284.37 km) |
| Sikeston to Melissa (Texas) | 465.64 mi (749.38 km) |
| Sikeston to Melrose (Massachusetts) | 1,055.15 mi (1,698.11 km) |
| Sikeston to Melrose Park (Illinois) | 358.67 mi (577.23 km) |
| Sikeston to Melville (New York) | 909.89 mi (1,464.32 km) |
| Sikeston to Melvindale (Michigan) | 505.09 mi (812.87 km) |
| Sikeston to Memphis (Florida) | 764.51 mi (1,230.36 km) |
| Sikeston to Memphis (Tennessee) | 124.57 mi (200.47 km) |
| Sikeston to Menasha (Wisconsin) | 509.89 mi (820.59 km) |
