| Sikeston to Merriam (Kansas) | 314.73 mi (506.51 km) |
| Sikeston to Merrick (New York) | 900.62 mi (1,449.41 km) |
| Sikeston to Merrifield (Virginia) | 686.54 mi (1,104.88 km) |
| Sikeston to Merrillville (Indiana) | 339.40 mi (546.22 km) |
| Sikeston to Merritt Island (Florida) | 786.68 mi (1,266.03 km) |
| Sikeston to Mesa (Arizona) | 1,270.25 mi (2,044.28 km) |
| Sikeston to Mesquite (Nevada) | 1,353.43 mi (2,178.13 km) |
| Sikeston to Mesquite (Texas) | 488.46 mi (786.10 km) |
| Sikeston to Metairie (Louisiana) | 477.11 mi (767.83 km) |
| Sikeston to Methuen Town (Massachusetts) | 1,054.03 mi (1,696.30 km) |
| Sikeston to Metuchen (New Jersey) | 857.52 mi (1,380.04 km) |
| Sikeston to Mexico (Missouri) | 200.49 mi (322.65 km) |
| Sikeston to Miami (Florida) | 944.67 mi (1,520.30 km) |
| Sikeston to Miami (Oklahoma) | 291.94 mi (469.83 km) |
| Sikeston to Miami Beach (Florida) | 945.19 mi (1,521.14 km) |
