| Sikeston to Mineola (New York) | 897.57 mi (1,444.50 km) |
| Sikeston to Mineral Wells (Texas) | 557.11 mi (896.58 km) |
| Sikeston to Minneapolis (Minnesota) | 590.11 mi (949.69 km) |
| Sikeston to Minnehaha (Washington) | 1,804.14 mi (2,903.48 km) |
| Sikeston to Minneola (Florida) | 731.21 mi (1,176.78 km) |
| Sikeston to Minnetonka (Minnesota) | 591.41 mi (951.79 km) |
| Sikeston to Minooka (Illinois) | 323.11 mi (520.00 km) |
| Sikeston to Minot (North Dakota) | 982.09 mi (1,580.51 km) |
| Sikeston to Mint Hill (North Carolina) | 512.77 mi (825.22 km) |
| Sikeston to Miramar (Florida) | 929.25 mi (1,495.48 km) |
| Sikeston to Mishawaka (Indiana) | 378.01 mi (608.35 km) |
| Sikeston to Mission (Texas) | 898.68 mi (1,446.29 km) |
| Sikeston to Mission Bend (Texas) | 607.99 mi (978.47 km) |
| Sikeston to Mission Viejo (California) | 1,593.99 mi (2,565.28 km) |
| Sikeston to Missoula (Montana) | 1,425.44 mi (2,294.02 km) |
