| Sikeston to Missouri City (Texas) | 611.38 mi (983.92 km) |
| Sikeston to Mitchell (South Dakota) | 648.66 mi (1,043.91 km) |
| Sikeston to Mitchellville (Maryland) | 709.92 mi (1,142.51 km) |
| Sikeston to Moberly (Missouri) | 233.58 mi (375.92 km) |
| Sikeston to Mobile (Alabama) | 437.10 mi (703.45 km) |
| Sikeston to Modesto (California) | 1,720.19 mi (2,768.39 km) |
| Sikeston to Mokena (Illinois) | 333.87 mi (537.31 km) |
| Sikeston to Moline (Illinois) | 321.27 mi (517.03 km) |
| Sikeston to Moncks Corner (South Carolina) | 599.09 mi (964.14 km) |
| Sikeston to Monfort Heights (Ohio) | 314.00 mi (505.34 km) |
| Sikeston to Monmouth (Oregon) | 1,826.94 mi (2,940.17 km) |
| Sikeston to Monroe (Georgia) | 393.56 mi (633.37 km) |
| Sikeston to Monroe (Louisiana) | 333.19 mi (536.21 km) |
| Sikeston to Monroe (Michigan) | 479.80 mi (772.16 km) |
| Sikeston to Monroe (North Carolina) | 521.19 mi (838.77 km) |
