| Sikeston to Pelham (Alabama) | 294.21 mi (473.48 km) |
| Sikeston to Pell City (Alabama) | 296.42 mi (477.04 km) |
| Sikeston to Pella (Iowa) | 359.63 mi (578.77 km) |
| Sikeston to Pembroke Pines (Florida) | 927.10 mi (1,492.02 km) |
| Sikeston to Pendleton (Oregon) | 1,623.48 mi (2,612.75 km) |
| Sikeston to Pensacola (Florida) | 466.04 mi (750.01 km) |
| Sikeston to Peoria (Arizona) | 1,294.75 mi (2,083.70 km) |
| Sikeston to Peoria (Illinois) | 267.16 mi (429.95 km) |
| Sikeston to Perris (California) | 1,566.70 mi (2,521.36 km) |
| Sikeston to Perry (Georgia) | 451.29 mi (726.28 km) |
| Sikeston to Perry Hall (Maryland) | 732.61 mi (1,179.02 km) |
| Sikeston to Perrysburg (Ohio) | 452.17 mi (727.70 km) |
| Sikeston to Perth Amboy (New Jersey) | 861.84 mi (1,387.00 km) |
| Sikeston to Peru (Indiana) | 327.63 mi (527.27 km) |
| Sikeston to Petal (Mississippi) | 383.15 mi (616.61 km) |
