| Sikeston to Pullman (Washington) | 1,564.00 mi (2,517.01 km) |
| Sikeston to Punta Gorda (Florida) | 819.07 mi (1,318.17 km) |
| Sikeston to Puyallup (Washington) | 1,806.03 mi (2,906.53 km) |
| Sikeston to Queen Creek (Arizona) | 1,267.95 mi (2,040.56 km) |
| Sikeston to Queens (New York) | 889.52 mi (1,431.55 km) |
| Sikeston to Quincy (Illinois) | 231.87 mi (373.16 km) |
| Sikeston to Quincy (Massachusetts) | 1,053.52 mi (1,695.48 km) |
| Sikeston to Raceland (Louisiana) | 498.20 mi (801.77 km) |
| Sikeston to Racine (Wisconsin) | 414.45 mi (667.00 km) |
| Sikeston to Radcliff (Kentucky) | 210.67 mi (339.04 km) |
| Sikeston to Radford (Virginia) | 498.28 mi (801.90 km) |
| Sikeston to Rahway (New Jersey) | 862.69 mi (1,388.37 km) |
| Sikeston to Raleigh (North Carolina) | 612.98 mi (986.49 km) |
| Sikeston to Ramona (California) | 1,562.22 mi (2,514.15 km) |
| Sikeston to Ramsey (Minnesota) | 612.51 mi (985.73 km) |
