| Sikeston to Salisbury (Maryland) | 772.26 mi (1,242.83 km) |
| Sikeston to Salisbury (New York) | 901.59 mi (1,450.98 km) |
| Sikeston to Salisbury (North Carolina) | 513.48 mi (826.36 km) |
| Sikeston to Salmon Creek (Washington) | 1,806.68 mi (2,907.57 km) |
| Sikeston to Salt Lake City (Utah) | 1,228.68 mi (1,977.37 km) |
| Sikeston to Sammamish (Washington) | 1,800.60 mi (2,897.78 km) |
| Sikeston to San Angelo (Texas) | 725.29 mi (1,167.24 km) |
| Sikeston to San Anselmo (California) | 1,801.64 mi (2,899.46 km) |
| Sikeston to San Antonio (Texas) | 727.36 mi (1,170.57 km) |
| Sikeston to San Benito (Texas) | 880.89 mi (1,417.65 km) |
| Sikeston to San Bernardino (California) | 1,564.19 mi (2,517.31 km) |
| Sikeston to San Bruno (California) | 1,797.67 mi (2,893.06 km) |
| Sikeston to San Buenaventura (California) | 1,668.82 mi (2,685.70 km) |
| Sikeston to San Carlos (California) | 1,790.13 mi (2,880.94 km) |
| Sikeston to San Carlos Park (Florida) | 851.20 mi (1,369.87 km) |
