| Sikeston to San Clemente (California) | 1,594.62 mi (2,566.29 km) |
| Sikeston to San Diego (California) | 1,580.33 mi (2,543.29 km) |
| Sikeston to San Diego Country Estates (California) | 1,558.08 mi (2,507.49 km) |
| Sikeston to San Dimas (California) | 1,593.22 mi (2,564.04 km) |
| Sikeston to San Fernando (California) | 1,624.66 mi (2,614.64 km) |
| Sikeston to San Francisco (California) | 1,797.09 mi (2,892.13 km) |
| Sikeston to San Gabriel (California) | 1,609.48 mi (2,590.20 km) |
| Sikeston to San Germán (Puerto Rico) | 1,886.87 mi (3,036.62 km) |
| Sikeston to San Jacinto (California) | 1,553.76 mi (2,500.54 km) |
| Sikeston to San Jose (California) | 1,769.47 mi (2,847.68 km) |
| Sikeston to San Juan (Puerto Rico) | 1,914.62 mi (3,081.28 km) |
| Sikeston to San Juan (Texas) | 893.70 mi (1,438.28 km) |
| Sikeston to San Juan Capistrano (California) | 1,596.06 mi (2,568.62 km) |
| Sikeston to San Leandro (California) | 1,782.16 mi (2,868.10 km) |
| Sikeston to San Lorenzo (California) | 1,781.05 mi (2,866.33 km) |
