| Sikeston to San Luis (Arizona) | 1,454.64 mi (2,341.01 km) |
| Sikeston to San Luis Obispo (California) | 1,731.64 mi (2,786.81 km) |
| Sikeston to San Marcos (California) | 1,576.86 mi (2,537.71 km) |
| Sikeston to San Marcos (Texas) | 682.58 mi (1,098.50 km) |
| Sikeston to San Marino (California) | 1,609.77 mi (2,590.67 km) |
| Sikeston to San Mateo (California) | 1,791.97 mi (2,883.90 km) |
| Sikeston to San Pablo (California) | 1,789.56 mi (2,880.01 km) |
| Sikeston to San Rafael (California) | 1,798.98 mi (2,895.18 km) |
| Sikeston to San Ramon (California) | 1,769.53 mi (2,847.79 km) |
| Sikeston to San Tan Valley (Arizona) | 1,266.36 mi (2,038.01 km) |
| Sikeston to Sand Springs (Oklahoma) | 366.83 mi (590.35 km) |
| Sikeston to Sandusky (Ohio) | 484.86 mi (780.31 km) |
| Sikeston to Sandy (Oregon) | 1,784.91 mi (2,872.53 km) |
| Sikeston to Sandy (Utah) | 1,223.21 mi (1,968.57 km) |
| Sikeston to Sandy Springs (Georgia) | 357.44 mi (575.24 km) |
