| Sikeston to Savage (Minnesota) | 578.25 mi (930.61 km) |
| Sikeston to Savannah (Georgia) | 584.35 mi (940.42 km) |
| Sikeston to Sayreville (New Jersey) | 858.42 mi (1,381.50 km) |
| Sikeston to Sayville (New York) | 926.05 mi (1,490.33 km) |
| Sikeston to Scaggsville (Maryland) | 708.23 mi (1,139.78 km) |
| Sikeston to Scarsdale (New York) | 894.25 mi (1,439.16 km) |
| Sikeston to Schaumburg (Illinois) | 364.43 mi (586.50 km) |
| Sikeston to Schenectady (New York) | 923.93 mi (1,486.92 km) |
| Sikeston to Schererville (Indiana) | 337.94 mi (543.86 km) |
| Sikeston to Schertz (Texas) | 711.17 mi (1,144.52 km) |
| Sikeston to Schiller Park (Illinois) | 362.30 mi (583.07 km) |
| Sikeston to Schofield Barracks (Hawaii) | 4,177.58 mi (6,723.16 km) |
| Sikeston to Scotchtown (New York) | 873.24 mi (1,405.34 km) |
| Sikeston to Scottdale (Georgia) | 368.20 mi (592.55 km) |
| Sikeston to Scotts Valley (California) | 1,781.10 mi (2,866.41 km) |
