| Sikeston to South Fulton (Georgia) | 361.15 mi (581.22 km) |
| Sikeston to South Gate (California) | 1,617.38 mi (2,602.93 km) |
| Sikeston to South Hill (Washington) | 1,805.01 mi (2,904.88 km) |
| Sikeston to South Holland (Illinois) | 342.46 mi (551.13 km) |
| Sikeston to South Houston (Texas) | 595.80 mi (958.85 km) |
| Sikeston to South Huntington (New York) | 911.32 mi (1,466.62 km) |
| Sikeston to South Jordan (Utah) | 1,229.82 mi (1,979.20 km) |
| Sikeston to South Lake Tahoe (California) | 1,655.26 mi (2,663.89 km) |
| Sikeston to South Laurel (Maryland) | 709.45 mi (1,141.75 km) |
| Sikeston to South Lyon (Michigan) | 497.77 mi (801.08 km) |
| Sikeston to South Miami (Florida) | 946.16 mi (1,522.70 km) |
| Sikeston to South Miami Heights (Florida) | 950.02 mi (1,528.91 km) |
| Sikeston to South Milwaukee (Wisconsin) | 426.29 mi (686.05 km) |
| Sikeston to South Ogden (Utah) | 1,232.90 mi (1,984.16 km) |
| Sikeston to South Pasadena (California) | 1,612.42 mi (2,594.94 km) |
