| Sikeston to Springfield (Missouri) | 205.37 mi (330.52 km) |
| Sikeston to Springfield (Ohio) | 377.47 mi (607.48 km) |
| Sikeston to Springfield (Oregon) | 1,810.00 mi (2,912.92 km) |
| Sikeston to Springfield (Tennessee) | 152.91 mi (246.08 km) |
| Sikeston to Springfield (Virginia) | 688.85 mi (1,108.60 km) |
| Sikeston to Springville (Utah) | 1,209.04 mi (1,945.76 km) |
| Sikeston to St. Albans (West Virginia) | 437.22 mi (703.63 km) |
| Sikeston to St. Andrews (South Carolina) | 515.67 mi (829.88 km) |
| Sikeston to St. Ann (Missouri) | 134.49 mi (216.44 km) |
| Sikeston to St. Augustine (Florida) | 678.50 mi (1,091.94 km) |
| Sikeston to St. Charles (Illinois) | 354.41 mi (570.37 km) |
| Sikeston to St. Charles (Missouri) | 141.35 mi (227.48 km) |
| Sikeston to St. Clair Shores (Michigan) | 525.65 mi (845.94 km) |
| Sikeston to St. Cloud (Florida) | 768.23 mi (1,236.35 km) |
| Sikeston to St. Cloud (Minnesota) | 643.03 mi (1,034.85 km) |
