| Sikeston to Vinings (Georgia) | 356.06 mi (573.03 km) |
| Sikeston to Virginia Beach (Virginia) | 748.69 mi (1,204.90 km) |
| Sikeston to Visalia (California) | 1,643.22 mi (2,644.50 km) |
| Sikeston to Vista (California) | 1,579.29 mi (2,541.63 km) |
| Sikeston to Wabash (Indiana) | 337.81 mi (543.66 km) |
| Sikeston to Waco (Texas) | 568.79 mi (915.39 km) |
| Sikeston to Waconia (Minnesota) | 591.76 mi (952.35 km) |
| Sikeston to Wade Hampton (South Carolina) | 428.89 mi (690.23 km) |
| Sikeston to Wadsworth (Ohio) | 509.62 mi (820.16 km) |
| Sikeston to Waggaman (Louisiana) | 481.51 mi (774.92 km) |
| Sikeston to Wahiawa (Hawaii) | 4,174.89 mi (6,718.84 km) |
| Sikeston to Waianae (Hawaii) | 4,185.17 mi (6,735.38 km) |
| Sikeston to Waihee-Waiehu (Hawaii) | 4,112.59 mi (6,618.58 km) |
| Sikeston to Wailuku (Hawaii) | 4,113.84 mi (6,620.59 km) |
| Sikeston to Waimalu (Hawaii) | 4,174.25 mi (6,717.80 km) |
