| Sikeston to Wayne (Michigan) | 497.50 mi (800.66 km) |
| Sikeston to Waynesboro (Pennsylvania) | 679.66 mi (1,093.80 km) |
| Sikeston to Waynesboro (Virginia) | 591.28 mi (951.58 km) |
| Sikeston to Weatherford (Oklahoma) | 515.43 mi (829.50 km) |
| Sikeston to Weatherford (Texas) | 544.68 mi (876.58 km) |
| Sikeston to Webb City (Missouri) | 269.78 mi (434.16 km) |
| Sikeston to Webster (Texas) | 600.04 mi (965.68 km) |
| Sikeston to Webster Groves (Missouri) | 124.78 mi (200.82 km) |
| Sikeston to Weddington (North Carolina) | 511.19 mi (822.68 km) |
| Sikeston to Weigelstown (Pennsylvania) | 722.13 mi (1,162.15 km) |
| Sikeston to Weirton (West Virginia) | 543.80 mi (875.16 km) |
| Sikeston to Wekiwa Springs (Florida) | 737.42 mi (1,186.76 km) |
| Sikeston to Welby (Colorado) | 856.56 mi (1,378.50 km) |
| Sikeston to Wellington (Colorado) | 869.74 mi (1,399.71 km) |
| Sikeston to Wellington (Florida) | 893.43 mi (1,437.83 km) |
