| Sikeston to Worthington (Ohio) | 418.51 mi (673.53 km) |
| Sikeston to Wright (Florida) | 476.10 mi (766.21 km) |
| Sikeston to Wyandanch (New York) | 911.75 mi (1,467.32 km) |
| Sikeston to Wyandotte (Michigan) | 502.52 mi (808.73 km) |
| Sikeston to Wylie (Texas) | 473.75 mi (762.43 km) |
| Sikeston to Wyndham (Virginia) | 660.19 mi (1,062.47 km) |
| Sikeston to Wyoming (Michigan) | 463.01 mi (745.14 km) |
| Sikeston to Wyomissing (Pennsylvania) | 771.87 mi (1,242.20 km) |
| Sikeston to Xenia (Ohio) | 362.02 mi (582.61 km) |
| Sikeston to Yakima (Washington) | 1,717.40 mi (2,763.89 km) |
| Sikeston to Yankton (South Dakota) | 585.45 mi (942.19 km) |
| Sikeston to Yauco (Puerto Rico) | 1,897.46 mi (3,053.67 km) |
| Sikeston to Yazoo City (Mississippi) | 281.85 mi (453.59 km) |
| Sikeston to Yeadon (Pennsylvania) | 803.15 mi (1,292.55 km) |
| Sikeston to Yelm (Washington) | 1,818.46 mi (2,926.53 km) |
