| Silver Spring to Enterprise (Nevada) | 2,089.01 mi (3,361.93 km) |
| Silver Spring to Enumclaw (Washington) | 2,304.20 mi (3,708.24 km) |
| Silver Spring to Ephrata (Pennsylvania) | 92.87 mi (149.47 km) |
| Silver Spring to Erie (Colorado) | 1,488.91 mi (2,396.17 km) |
| Silver Spring to Erie (Pennsylvania) | 268.22 mi (431.66 km) |
| Silver Spring to Erlanger (Kentucky) | 406.09 mi (653.54 km) |
| Silver Spring to Escanaba (Michigan) | 692.79 mi (1,114.94 km) |
| Silver Spring to Escondido (California) | 2,254.75 mi (3,628.68 km) |
| Silver Spring to Española (New Mexico) | 1,598.75 mi (2,572.94 km) |
| Silver Spring to Essex (Maryland) | 37.14 mi (59.77 km) |
| Silver Spring to Essex Junction (Vermont) | 429.18 mi (690.69 km) |
| Silver Spring to Estelle (Louisiana) | 976.02 mi (1,570.75 km) |
| Silver Spring to Estero (Florida) | 911.73 mi (1,467.28 km) |
| Silver Spring to Euclid (Ohio) | 296.83 mi (477.70 km) |
| Silver Spring to Eufaula (Alabama) | 669.86 mi (1,078.03 km) |
