| Silver Spring to Southern Pines (North Carolina) | 294.16 mi (473.41 km) |
| Silver Spring to Southfield (Michigan) | 405.17 mi (652.05 km) |
| Silver Spring to Southgate (Michigan) | 392.53 mi (631.72 km) |
| Silver Spring to Southlake (Texas) | 1,197.42 mi (1,927.07 km) |
| Silver Spring to Spanaway (Washington) | 2,324.89 mi (3,741.55 km) |
| Silver Spring to Spanish Fork (Utah) | 1,834.12 mi (2,951.74 km) |
| Silver Spring to Spanish Lake (Missouri) | 708.66 mi (1,140.48 km) |
| Silver Spring to Spanish Springs (Nevada) | 2,257.96 mi (3,633.83 km) |
| Silver Spring to Sparks (Nevada) | 2,261.66 mi (3,639.79 km) |
| Silver Spring to Spartanburg (South Carolina) | 389.65 mi (627.08 km) |
| Silver Spring to Spearfish (South Dakota) | 1,425.20 mi (2,293.64 km) |
| Silver Spring to Speedway (Indiana) | 495.47 mi (797.38 km) |
| Silver Spring to Spencer (Iowa) | 984.63 mi (1,584.60 km) |
| Silver Spring to Spokane (Washington) | 2,090.99 mi (3,365.12 km) |
| Silver Spring to Spokane Valley (Washington) | 2,081.75 mi (3,350.25 km) |
