| Simi Valley to Shoreham-by-Sea | 5,471.00 mi (8,804.73 km) |
| Simi Valley to Shotley Bridge | 5,236.87 mi (8,427.93 km) |
| Simi Valley to Shrewsbury | 5,305.88 mi (8,538.98 km) |
| Simi Valley to Sidcup | 5,455.43 mi (8,779.67 km) |
| Simi Valley to Sidmouth | 5,380.62 mi (8,659.27 km) |
| Simi Valley to Sileby | 5,357.01 mi (8,621.27 km) |
| Simi Valley to Sittingbourne | 5,479.68 mi (8,818.69 km) |
| Simi Valley to Skegness | 5,382.86 mi (8,662.88 km) |
| Simi Valley to Skelmersdale | 5,267.64 mi (8,477.45 km) |
| Simi Valley to Skipton | 5,272.85 mi (8,485.83 km) |
| Simi Valley to Sleaford | 5,366.44 mi (8,636.45 km) |
| Simi Valley to Slough | 5,429.61 mi (8,738.12 km) |
| Simi Valley to Small Heath | 5,345.57 mi (8,602.87 km) |
| Simi Valley to Smethwick | 5,340.57 mi (8,594.82 km) |
| Simi Valley to Snaresbrook | 5,445.15 mi (8,763.13 km) |
