| Simi Valley to Des Plaines (Illinois) | 1,748.97 mi (2,814.69 km) |
| Simi Valley to Desert Hot Springs (California) | 128.02 mi (206.03 km) |
| Simi Valley to DeSoto (Texas) | 1,264.75 mi (2,035.41 km) |
| Simi Valley to Destin (Florida) | 1,895.40 mi (3,050.35 km) |
| Simi Valley to Destrehan (Louisiana) | 1,681.67 mi (2,706.39 km) |
| Simi Valley to Detroit (Michigan) | 1,995.68 mi (3,211.73 km) |
| Simi Valley to Diamond Bar (California) | 56.46 mi (90.86 km) |
| Simi Valley to Diamond Springs (California) | 327.06 mi (526.36 km) |
| Simi Valley to Dickinson (North Dakota) | 1,204.61 mi (1,938.64 km) |
| Simi Valley to Dickinson (Texas) | 1,425.83 mi (2,294.66 km) |
| Simi Valley to Dickson (Tennessee) | 1,769.29 mi (2,847.39 km) |
| Simi Valley to Difficult Run (Virginia) | 2,299.42 mi (3,700.56 km) |
| Simi Valley to Dinuba (California) | 161.66 mi (260.16 km) |
| Simi Valley to Discovery Bay (California) | 297.58 mi (478.90 km) |
| Simi Valley to Dix Hills (New York) | 2,500.35 mi (4,023.92 km) |
