| Simi Valley to Effingham (Illinois) | 1,698.11 mi (2,732.85 km) |
| Simi Valley to Eggertsville (New York) | 2,215.82 mi (3,566.02 km) |
| Simi Valley to Egypt Lake-Leto (Florida) | 2,174.47 mi (3,499.47 km) |
| Simi Valley to El Cajon (California) | 144.40 mi (232.38 km) |
| Simi Valley to El Campo (Texas) | 1,363.24 mi (2,193.92 km) |
| Simi Valley to El Centro (California) | 210.23 mi (338.33 km) |
| Simi Valley to El Cerrito (California) | 321.00 mi (516.59 km) |
| Simi Valley to El Dorado (Arkansas) | 1,496.35 mi (2,408.14 km) |
| Simi Valley to El Dorado (Kansas) | 1,244.17 mi (2,002.30 km) |
| Simi Valley to El Dorado Hills (California) | 330.30 mi (531.56 km) |
| Simi Valley to El Mirage (Arizona) | 371.05 mi (597.14 km) |
| Simi Valley to El Monte (California) | 43.25 mi (69.60 km) |
| Simi Valley to El Paso (Texas) | 732.18 mi (1,178.33 km) |
| Simi Valley to El Paso de Robles (California) | 143.74 mi (231.33 km) |
| Simi Valley to El Reno (Oklahoma) | 1,178.76 mi (1,897.03 km) |
