| Simi Valley to Elyria (Ohio) | 2,043.10 mi (3,288.05 km) |
| Simi Valley to Emeryville (California) | 316.33 mi (509.09 km) |
| Simi Valley to Emmaus (Pennsylvania) | 2,388.77 mi (3,844.35 km) |
| Simi Valley to Emporia (Kansas) | 1,284.07 mi (2,066.50 km) |
| Simi Valley to Encinitas (California) | 119.98 mi (193.08 km) |
| Simi Valley to Endicott (New York) | 2,354.90 mi (3,789.84 km) |
| Simi Valley to Endwell (New York) | 2,357.03 mi (3,793.27 km) |
| Simi Valley to Englewood (Colorado) | 844.27 mi (1,358.72 km) |
| Simi Valley to Englewood (Florida) | 2,209.63 mi (3,556.06 km) |
| Simi Valley to Englewood (New Jersey) | 2,466.73 mi (3,969.82 km) |
| Simi Valley to Englewood (Ohio) | 1,925.46 mi (3,098.73 km) |
| Simi Valley to Enid (Oklahoma) | 1,183.73 mi (1,905.03 km) |
| Simi Valley to Ennis (Texas) | 1,281.61 mi (2,062.56 km) |
| Simi Valley to Ensley (Florida) | 1,846.97 mi (2,972.41 km) |
| Simi Valley to Enterprise (Alabama) | 1,913.43 mi (3,079.36 km) |
