| Simi Valley to Oskaloosa (Iowa) | 1,499.34 mi (2,412.96 km) |
| Simi Valley to Oswego (Illinois) | 1,723.55 mi (2,773.78 km) |
| Simi Valley to Oswego (New York) | 2,332.88 mi (3,754.41 km) |
| Simi Valley to Otsego (Minnesota) | 1,526.45 mi (2,456.58 km) |
| Simi Valley to Ottawa (Illinois) | 1,695.64 mi (2,728.86 km) |
| Simi Valley to Ottawa (Kansas) | 1,335.45 mi (2,149.20 km) |
| Simi Valley to Ottumwa (Iowa) | 1,507.45 mi (2,426.01 km) |
| Simi Valley to Overland (Missouri) | 1,599.38 mi (2,573.95 km) |
| Simi Valley to Overland Park (Kansas) | 1,368.39 mi (2,202.20 km) |
| Simi Valley to Overlea (Maryland) | 2,340.94 mi (3,767.38 km) |
| Simi Valley to Oviedo (Florida) | 2,234.55 mi (3,596.16 km) |
| Simi Valley to Owasso (Oklahoma) | 1,297.17 mi (2,087.59 km) |
| Simi Valley to Owatonna (Minnesota) | 1,517.43 mi (2,442.06 km) |
| Simi Valley to Owensboro (Kentucky) | 1,775.72 mi (2,857.74 km) |
| Simi Valley to Owings Mills (Maryland) | 2,326.10 mi (3,743.49 km) |
