| Simi Valley to Sacramento (California) | 333.41 mi (536.57 km) |
| Simi Valley to Saddlebrooke (Arizona) | 469.14 mi (755.00 km) |
| Simi Valley to Safety Harbor (Florida) | 2,163.85 mi (3,482.38 km) |
| Simi Valley to Saginaw (Michigan) | 1,960.04 mi (3,154.38 km) |
| Simi Valley to Saginaw (Texas) | 1,232.62 mi (1,983.72 km) |
| Simi Valley to Sahuarita (Arizona) | 478.35 mi (769.83 km) |
| Simi Valley to Saks (Alabama) | 1,876.63 mi (3,020.15 km) |
| Simi Valley to Salem (Massachusetts) | 2,617.19 mi (4,211.96 km) |
| Simi Valley to Salem (Ohio) | 2,107.92 mi (3,392.37 km) |
| Simi Valley to Salem (Oregon) | 770.41 mi (1,239.85 km) |
| Simi Valley to Salem (Virginia) | 2,163.94 mi (3,482.52 km) |
| Simi Valley to Salem Lakes (Wisconsin) | 1,742.34 mi (2,804.02 km) |
| Simi Valley to Salida (California) | 271.27 mi (436.57 km) |
| Simi Valley to Salina (Kansas) | 1,211.49 mi (1,949.71 km) |
| Simi Valley to Salinas (California) | 233.02 mi (375.02 km) |
