| Simi Valley to San Clemente (California) | 86.32 mi (138.92 km) |
| Simi Valley to San Diego (California) | 136.40 mi (219.51 km) |
| Simi Valley to San Diego Country Estates (California) | 142.38 mi (229.14 km) |
| Simi Valley to San Dimas (California) | 54.82 mi (88.23 km) |
| Simi Valley to San Fernando (California) | 17.93 mi (28.85 km) |
| Simi Valley to San Francisco (California) | 317.43 mi (510.85 km) |
| Simi Valley to San Gabriel (California) | 38.99 mi (62.76 km) |
| Simi Valley to San Germán (Puerto Rico) | 3,356.23 mi (5,401.33 km) |
| Simi Valley to San Jacinto (California) | 105.72 mi (170.14 km) |
| Simi Valley to San Jose (California) | 272.25 mi (438.15 km) |
| Simi Valley to San Juan (Puerto Rico) | 3,401.34 mi (5,473.93 km) |
| Simi Valley to San Juan (Texas) | 1,346.87 mi (2,167.58 km) |
| Simi Valley to San Juan Capistrano (California) | 82.09 mi (132.12 km) |
| Simi Valley to San Leandro (California) | 304.73 mi (490.42 km) |
| Simi Valley to San Lorenzo (California) | 301.99 mi (486.00 km) |
