| Simi Valley to Sanford (Florida) | 2,226.47 mi (3,583.15 km) |
| Simi Valley to Sanford (Maine) | 2,620.96 mi (4,218.03 km) |
| Simi Valley to Sanford (North Carolina) | 2,229.52 mi (3,588.07 km) |
| Simi Valley to Sanger (California) | 174.13 mi (280.23 km) |
| Simi Valley to Santa Ana (California) | 61.69 mi (99.28 km) |
| Simi Valley to Santa Barbara (California) | 56.52 mi (90.97 km) |
| Simi Valley to Santa Clara (California) | 279.88 mi (450.42 km) |
| Simi Valley to Santa Clara (Oregon) | 719.60 mi (1,158.08 km) |
| Simi Valley to Santa Clarita (California) | 17.80 mi (28.64 km) |
| Simi Valley to Santa Cruz (California) | 262.98 mi (423.23 km) |
| Simi Valley to Santa Fe (New Mexico) | 728.78 mi (1,172.86 km) |
| Simi Valley to Santa Fe (Texas) | 1,425.02 mi (2,293.35 km) |
| Simi Valley to Santa Fe Springs (California) | 45.53 mi (73.28 km) |
| Simi Valley to Santa Maria (California) | 106.80 mi (171.88 km) |
| Simi Valley to Santa Monica (California) | 22.72 mi (36.57 km) |
