| Simi Valley to Santa Paula (California) | 19.07 mi (30.69 km) |
| Simi Valley to Santa Rosa (California) | 363.08 mi (584.32 km) |
| Simi Valley to Santaquin (Utah) | 549.34 mi (884.08 km) |
| Simi Valley to Santee (California) | 140.77 mi (226.54 km) |
| Simi Valley to Sapulpa (Oklahoma) | 1,282.46 mi (2,063.93 km) |
| Simi Valley to Saraland (Alabama) | 1,793.58 mi (2,886.50 km) |
| Simi Valley to Sarasota (Florida) | 2,189.28 mi (3,523.31 km) |
| Simi Valley to Sarasota Springs (Florida) | 2,193.96 mi (3,530.84 km) |
| Simi Valley to Saratoga (California) | 277.06 mi (445.88 km) |
| Simi Valley to Saratoga Springs (New York) | 2,469.88 mi (3,974.89 km) |
| Simi Valley to Saratoga Springs (Utah) | 563.04 mi (906.13 km) |
| Simi Valley to Sartell (Minnesota) | 1,508.52 mi (2,427.73 km) |
| Simi Valley to Satellite Beach (Florida) | 2,279.31 mi (3,668.20 km) |
| Simi Valley to Sauk Rapids (Minnesota) | 1,510.95 mi (2,431.64 km) |
| Simi Valley to Sault Ste. Marie (Michigan) | 1,976.20 mi (3,180.38 km) |
