| Simi Valley to Storm Lake (Iowa) | 1,393.46 mi (2,242.56 km) |
| Simi Valley to Storrs (Connecticut) | 2,551.47 mi (4,106.19 km) |
| Simi Valley to Stoughton (Wisconsin) | 1,692.30 mi (2,723.49 km) |
| Simi Valley to Stow (Ohio) | 2,077.62 mi (3,343.61 km) |
| Simi Valley to Streamwood (Illinois) | 1,734.75 mi (2,791.81 km) |
| Simi Valley to Streator (Illinois) | 1,693.57 mi (2,725.54 km) |
| Simi Valley to Streetsboro (Ohio) | 2,082.31 mi (3,351.16 km) |
| Simi Valley to Strongsville (Ohio) | 2,057.21 mi (3,310.77 km) |
| Simi Valley to Stuart (Florida) | 2,324.11 mi (3,740.29 km) |
| Simi Valley to Stuarts Draft (Virginia) | 2,214.18 mi (3,563.37 km) |
| Simi Valley to Sturgis (Michigan) | 1,874.00 mi (3,015.92 km) |
| Simi Valley to Suamico (Wisconsin) | 1,773.19 mi (2,853.67 km) |
| Simi Valley to Sudley (Virginia) | 2,292.14 mi (3,688.85 km) |
| Simi Valley to Suffern (New York) | 2,456.92 mi (3,954.04 km) |
| Simi Valley to Suffolk (Virginia) | 2,356.15 mi (3,791.86 km) |
