| Simi Valley to Superior (Colorado) | 843.82 mi (1,358.00 km) |
| Simi Valley to Superior (Wisconsin) | 1,631.48 mi (2,625.61 km) |
| Simi Valley to Surprise (Arizona) | 363.03 mi (584.24 km) |
| Simi Valley to Susanville (California) | 437.35 mi (703.84 km) |
| Simi Valley to Sussex (Wisconsin) | 1,744.61 mi (2,807.68 km) |
| Simi Valley to Suwanee (Georgia) | 1,973.09 mi (3,175.38 km) |
| Simi Valley to Swansea (Illinois) | 1,619.71 mi (2,606.68 km) |
| Simi Valley to Sweetwater (Florida) | 2,354.44 mi (3,789.10 km) |
| Simi Valley to Sweetwater (Texas) | 1,064.07 mi (1,712.45 km) |
| Simi Valley to Sycamore (Illinois) | 1,708.87 mi (2,750.17 km) |
| Simi Valley to Sylacauga (Alabama) | 1,860.62 mi (2,994.37 km) |
| Simi Valley to Sylvania (Ohio) | 1,961.38 mi (3,156.54 km) |
| Simi Valley to Syosset (New York) | 2,491.70 mi (4,010.01 km) |
| Simi Valley to Syracuse (New York) | 2,350.44 mi (3,782.67 km) |
| Simi Valley to Syracuse (Utah) | 595.76 mi (958.79 km) |
