| Siracusa to Somma Lombardo | 685.64 mi (1,103.42 km) |
| Siracusa to Somma Vesuviana | 266.72 mi (429.25 km) |
| Siracusa to Sommacampagna | 619.81 mi (997.48 km) |
| Siracusa to Sona | 622.24 mi (1,001.40 km) |
| Siracusa to Sondrio | 687.82 mi (1,106.93 km) |
| Siracusa to Sora | 333.25 mi (536.32 km) |
| Siracusa to Sorbolo | 593.43 mi (955.03 km) |
| Siracusa to Soresina | 633.74 mi (1,019.91 km) |
| Siracusa to Sorisole | 665.81 mi (1,071.51 km) |
| Siracusa to Sorrento | 250.74 mi (403.53 km) |
| Siracusa to Sorso | 443.01 mi (712.96 km) |
| Siracusa to Sortino | 15.54 mi (25.01 km) |
| Siracusa to Soverato Marina | 131.06 mi (210.93 km) |
| Siracusa to Sovicille | 479.59 mi (771.82 km) |
| Siracusa to Spello | 431.72 mi (694.78 km) |
