| Siracusa to Sangeorz-Bai | 857.39 mi (1,379.84 km) |
| Siracusa to Sannicolau Mare | 679.29 mi (1,093.21 km) |
| Siracusa to Santana | 716.29 mi (1,152.75 km) |
| Siracusa to Satu Mare | 835.09 mi (1,343.94 km) |
| Siracusa to Scobinti | 926.81 mi (1,491.56 km) |
| Siracusa to Scornicesti | 708.41 mi (1,140.08 km) |
| Siracusa to Sebes | 748.06 mi (1,203.89 km) |
| Siracusa to Seini | 842.04 mi (1,355.14 km) |
| Siracusa to Sfantu-Gheorghe | 813.91 mi (1,309.86 km) |
| Siracusa to Sibiu | 756.72 mi (1,217.82 km) |
| Siracusa to Sighetu Marmatiei | 867.71 mi (1,396.45 km) |
| Siracusa to Sighisoara | 798.94 mi (1,285.76 km) |
| Siracusa to Simeria | 725.83 mi (1,168.10 km) |
| Siracusa to Sinaia | 781.04 mi (1,256.96 km) |
| Siracusa to Slatina | 695.09 mi (1,118.64 km) |
