| Skopje to Sangeorz-Bai | 404.04 mi (650.25 km) |
| Skopje to Sannicolau Mare | 283.96 mi (456.99 km) |
| Skopje to Santana | 300.84 mi (484.16 km) |
| Skopje to Satu Mare | 406.61 mi (654.38 km) |
| Skopje to Scobinti | 459.71 mi (739.84 km) |
| Skopje to Scornicesti | 237.08 mi (381.55 km) |
| Skopje to Sebes | 293.76 mi (472.76 km) |
| Skopje to Seini | 407.60 mi (655.97 km) |
| Skopje to Sfantu-Gheorghe | 343.96 mi (553.54 km) |
| Skopje to Sibiu | 295.18 mi (475.05 km) |
| Skopje to Sighetu Marmatiei | 427.12 mi (687.39 km) |
| Skopje to Sighisoara | 335.82 mi (540.45 km) |
| Skopje to Simeria | 277.61 mi (446.76 km) |
| Skopje to Sinaia | 309.89 mi (498.72 km) |
| Skopje to Slatina | 223.75 mi (360.09 km) |
